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Duan, Lei
One or more keywords matched the following items that are connected to Duan, Lei
Item TypeName
Concept Protein Kinase C
Concept Protein Kinase Inhibitors
Concept Proto-Oncogene Proteins c-akt
Academic Article Modeling breast cancer-associated c-Src and EGFR overexpression in human MECs: c-Src and EGFR cooperatively promote aberrant three-dimensional acinar structure and invasive behavior.
Academic Article Overexpression of RhoA induces preneoplastic transformation of primary mammary epithelial cells.
Academic Article The prolyl peptidases PRCP/PREP regulate IRS-1 stability critical for rapamycin-induced feedback activation of PI3K and AKT.
Academic Article Increasing cisplatin sensitivity by schedule-dependent inhibition of AKT and Chk1.
Academic Article Crosstalk between the IGF-1R/AKT/mTORC1 pathway and the tumor suppressors p53 and p27 determines cisplatin sensitivity and limits the effectiveness of an IGF-1R pathway inhibitor.
Academic Article The IGF-1R/AKT pathway has opposing effects on Nutlin-3a-induced apoptosis.
Academic Article p53 promotes AKT and SP1-dependent metabolism through the pentose phosphate pathway that inhibits apoptosis in response to Nutlin-3a.
Academic Article Prolyl endopeptidase inhibitor Y-29794 blocks the IRS1-AKT-mTORC1 pathway and inhibits survival and in vivo tumor growth of triple-negative breast cancer.
Academic Article Fatty acid oxidation and autophagy promote endoxifen resistance and counter the effect of AKT inhibition in ER-positive breast cancer cells.
Academic Article Mixed lineage kinase 3 and CD70 cooperation sensitize trastuzumab-resistant HER2+ breast cancer by ceramide-loaded nanoparticles.
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  • Proto Oncogene Proteins c akt